Santin, A., Spatola Rossi, T., Morlino, M.S., Favaro, L., Pankaj Gupte, A., Morosinotto, T., Treu, L., Campanaro, S., 2024. Autotrophic poly-3-hydroxybutyrate accumulation in Cupriavidus necator for sustainable bioplastic production triggered by nutrient starvation. Bioresource Technology, 406, 131068 (2024).
CooCE partners involved: UNIPD
A new study by UNIPD partners has been recently published in Bioresource Technology. The work, led by Dr. Anna Santin and Dr. Tatiana Spatola Rossi, investigates the impact of various nutrient stress conditions on PHB accumulation in C. necator DSM545 using CO2 as the sole carbon source. The nutrients tested include nitrogen, phosphorus, oxygen, and magnesium, which are critically compared to assess their effectiveness in enhancing polymer production. Results identify nitrogen starvation as the nutritional stress associated with highest intracellular PHB accumulation and CO2 conversion efficiency. Additionally, the role of effective gas-liquid transfer efficiency in polymer accumulation is highlighted. Check out the paper here