Santin, A., Collura, F., Singh, G., Morlino, M.S., Bizzotto, E., Bellan, A., Gupte, A.P., Favaro, L., Campanaro, S., Treu, L., Morosinotto, T. . Deciphering the genetic landscape of enhanced poly-3-hydroxybutyrate production in Synechocystis sp. B12. Biotechnology for Biofuels and Bioproducts 17, 101 (2024).
CooCE partners involved: UNIPD

A recent study by UNIPD partners has been recently published in Biotechnology for Biofuels and Bioproducts. The work, led by Dr. Anna Santin, investigates the molecular bases of the superior ability of the cyanobacterium Synechocystis sp. B12 to accumulate high levels of poly-hydroxybutyrate (PHB) under the challenging conditions of high light intensity and nitrogen deprivation. We employed advanced genomic and transcriptomic analyses to unravel the molecular bases of this capacity, and we identified strain-specific and differentially regulated key genes involved in conferring high-light adaptability and enhanced PHB production. Check out the paper here.