Spatola Rossi, T., Francescato L., Treu, L., Campanaro, S. Genetic engineering of Cupriavidus necator’s autotrophic metabolism for enhanced CO2 capture and polyhydroxybutyrate (PHB) synthesis. 7th Applied Synthetic Biology in Europe Conference. 6-8 November 2024. Brno, Czech Republic
-> CooCE partners involved: UNIPD

During the 7th Applied Synthetic Biology in Europe Conference, Dr. Spatola Rossi presented the work on the optimisation of nutrient stress conditions to enhance polyhydroxybutyrate (PHB) production in Cupriavidus necator DSM 545, and genetic engineering approaches to enhance CO2 capture and PHB production in C. necator. The results highlighted preliminary work on the performance of overexpression mutants expressing key genes from the microorganism’s autotrophic metabolism. The research was carried out in the University of Padova as part of the CooCE Project and BioCO2-Trapping Project.