The facultative chemolithotroph Cupriavidus necator is employed in the CooCE project for CO2 bioconversion to polyhydroxyalkanoates (PHA). A recent review article by Maria Silvia Morlino from UniPD summarizes relevant knowledge on this bacterial platform and highlights some areas of interest for further research. In particular, an overview on strain variability is given, with a remark on the limited knowledge regarding several mutants; given a detailed explanation of the bacterium’s physiology, possible circular economy applications, including those regarding CO2 utilization; and finally, the reivew presents a recapitulation of metabolic models which have been developed around C. necator’s metabolism, showcasing the potential of these tools for process optimization. This work is foundational for the identification of further areas of research and will help accelerate the development of C. necator-based bioprocesses.

Link to the DOI here.

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